High Creatinine Levels: Symptoms and Causes
What are normal creatinine levels for adults?
Creatinine is determined in a regularly purchased blood test, and it’s a reflection of basic metabolic health. Normal creatinine bloods levels for men are about 0.6 to 1.2 milligrams/deciliters (mg/dL) and 0.5 to 1.1 mg/dL for women. Creatinine is a chemical waste product discovered in the blood– a byproduct of normal, daily contraction. Under regular conditions, it’s filtered by the kidneys and removed from the body through urination.
What Causes High Creatinine Levels?
Temporary elevated levels may take place, regardless of kidney function, due to taking certain supplements or medications, dehydration, consuming big quantities of meat or protein or through building muscle through heavy weight training.
Kidney Disease and High Creatinine Levels
Abnormally high levels of creatinine might indicate kidney damage or chronic kidney disease. Practical damage to the kidneys can be due to a serious infection or low blood circulation to the kidneys. Decreased blood circulation or low blood pressure can be a result of heart failure, artery disease or severe dehydration.
Another cause is the loss of the architectural units where filtering is performed– the glomerulus. An increase in blood creatinine and minimized excretion are signs of lost kidney glomerular function– or glomerular purification rate. Diseases that impact the microscopic capillary in the glomerulus, such as diabetes, or inflammatory or autoimmune illness of the kidney, such as lupus, can damage the fragile structures involved in kidney filtering, according to iytmed.com. Some acquired conditions (such as Goodpasture syndrome), reaction to contagious agents (such as Streptococcus) and damage caused by medications can likewise reduce kidney function.
Other conditions that can result in harm include:
Symptoms of High Creatinine Levels
Some individuals with high creatinine levels may experience the following symptoms:
- Shortness of breath
Factors That Can Affect Creatinine Test Results
- Medications: phenytoin, vitamin C, diuretics, some antibiotics, cimetidine and quinine
- Doing exhausting workout two days prior to screening
- Eating high amounts of meat (eight ounces) within 24 hours of testing
Urinary Tract Obstruction and High Creatinine Levels
Another way kidney filtering may suffer is when something blocks urine circulation from the kidney. A clog in the urinary tract, specifically the ureter (which transfers fluid from the kidney to the bladder), the bladder itself or the urethra, will obstruct the circulation. Conditions that may block the urinary system include kidney stones, hereditary blockages, post-injury or postsurgical scarring, bad bladder emptying (aka benign prostatic hypertrophy– BPH) or due to prostate cancer. Blood test results are typically typical– particularly if there is just partial obstruction– however tests may reveal high levels of creatinine if there has been a total obstruction for more than several hours.
Sources of Creatinine
In addition to production in the skeletal muscle of the body, creatine and creatinine are likewise present in the diet in meat. Vegetarians have lower consumption of these substances than people eating a diet high in animal flesh, especially beef. Creatine is a molecule that acts as a muscle’s shop of energy and breaks down into creatinine. People looking for to boost muscle efficiency in some cases take creatine supplements, such as creatine salts or creatine esters. High intake of dietary or extra sources of creatine may increase the rate of creatinine production, elevate plasma creatinine and increase creatinine in the urine.
Last modified: September 7, 2016