Type 2 Diabetes and Kidney Disease


Nephropathy, or kidney disease, is among the most severe issues for lots of people with diabetes. It’s the leading reason for kidney failure in the United States. According to the National Kidney Structure, more than 660,000 Americans have end-stage kidney disease and are living by means of dialysis. Nephropathy has couple of early signs or alerting signs, comparable to other diseases associated with type 2 diabetes. Damage to the kidneys from nephropathy can happen for as long as a decade before the first signs appear.

Symptoms of Nephropathy

Frequently, no signs of kidney disease appear up until the kidneys are no longer operating correctly. Symptoms that indicate your kidneys could be at risk consist of:

  • fluid retention
  • swelling of the feet, ankles, and legs
  • a poor cravings
  • feeling exhausted and weak most of the time
  • frequent headaches
  • indigestion
  • queasiness
  • vomiting
  • insomnia
  • difficulty concentrating

Danger Aspects for Diabetic Nephropathy

Early diagnosis of kidney disease is essential for maintaining health. If you have prediabetes, type 2 diabetes, or other recognized diabetes risk aspects, your kidneys are already overworked and their function ought to be checked annually.

Besides diabetes, other risk factors for kidney disease are:

  • uncontrolled high blood pressure
  • uncontrolled high blood glucose
  • obesity
  • high cholesterol
  • a family history of kidney disease
  • a family history of heart disease
  • smoking
  • advanced age

A higher prevalence of kidney disease exists among:

  • African Americans
  • American Indians
  • Hispanic Americans
  • Asian Americans

Causes of Diabetic Nephropathy

Kidney disease doesn’t have just one particular cause. Experts believe its advancement is most likely associated with years of uncontrolled blood glucose. Other aspects likely play important roles as well, such as genetic predisposition.

The kidneys are the body’s blood filtration system. Each is comprised of hundreds of countless nephrons that clean up the blood of waste.

Gradually, specifically when a person has type 2 diabetes, the kidneys become overworked because they’re continuously removing excess glucose from the blood. The nephrons end up being swollen and scarred, and they no longer work as well.

Quickly, the nephrons can no longer totally filter the body’s blood supply. Material that would normally be eliminated from the blood, such as protein, enters the urine.

Much of that undesirable material is a protein called albumin. Your body’s levels of albumin can be tested in a urine sample to help determine how your kidneys are operating.

Information verified by the iytmed.com team.

A small amount of albumin in the urine is described as microalbuminuria. When larger quantities of albumin are discovered in the urine, the condition is called macroalbuminuria.

The risks of kidney failure are much higher with macroalbuminuria, and end-stage renal disease (ESRD) is a risk. Treatment for ERSD is dialysis, or having your blood filtered by a maker and pumped back into your body.

Preventing Diabetic Nephropathy

The main methods to prevent diabetic nephropathy include the following:


The best method to protect kidney health is to view your diet thoroughly. People with diabetes who have partial kidney function require to be much more vigilant about preserving:

  • healthy blood glucose
  • blood cholesterol
  • lipid levels

Preserving a high blood pressure of less than 130/80 is also vital. Even if you have mild kidney disease, it might be made much even worse by hypertension. Follow these tips to assist decrease your blood pressure:

  • Eat foods low in salt.
  • Don’t include salt to meals.
  • Lose weight if you’re overweight.
  • Avoid alcohol.

Your doctor might advise that you follow a low-fat, low-protein diet.


Based upon your doctor’s recommendations, daily exercise is likewise essential.


Many people with type 2 diabetes who have high blood pressure take angiotensin transforming enzyme (ACE) inhibitors for heart disease treatment, such as captopril and enalapril. These drugs also have the prospective to slow the development of kidney disease.

Doctors also frequently recommend angiotensin receptor blockers.

Other possible options for individuals with type 2 diabetes and chronic kidney disease could be the use of a sodium-glucose cotransporter-2 inhibitor or a glucagon-like peptide-1 receptor agonist. These drugs can decrease the threat of chronic kidney disease development and cardiovascular occasions.

Stopping Smoking

If you smoke cigarettes, you should stop right away. According to a 2012 research study published in the American Journal of Medical Science, cigarette smoking is an established danger aspect for developing kidney disease.

Ali Gadimov
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