Hormone Replacement Therapy and Risk of Weight Gain

Why You Need Hormone Replacement Therapy (HRT)?

HRT, also called hormone therapy (HT) or menopause hormone therapy (MHT), is medication consisting of hormones that a woman’s body stops producing after menopause. HRT is used to deal with menopausal symptoms.

While HRT decreases the likelihood of some debilitating diseases such as osteoporosis, colorectal (bowel) cancer and heart disease, it might enhance the chances of establishing an embolism (when given up tablet form) or breast cancer (when some types are used long-lasting).

For women who experience menopause prior to the age of 45 (early or premature menopause), HRT is strongly suggested till the average age of menopause onset (around 51 years), unless there is a particular reason for a female not to take it.

Advantages of HRT

HRT decreases the risk of various chronic conditions that can impact postmenopausal women, consisting of:

Diabetes: taking HRT around the time of menopause lowers women’s risk of establishing diabetes.

Osteoporosis: is damaging of bones such that they break more easily. HRT avoids further bone density loss, protecting bone integrity and reducing the risk of fractures, but it is not typically suggested as the first choice of treatment, other than in more youthful postmenopausal women (under the age of 60).

Bowel cancer: HRT slightly lowers the risk of colorectal cancer (bowel cancer).

Does hormone therapy cause weight gain?

Fear of weight gain is among the primary factors adding to the bad compliance seen with hormone replacement therapy (HRT). Although an increase in weight can be an outcome of rehydration, (which in turn may relieve some of the results of skin aging), lots of women consider weight gain to be cosmetically unacceptable.

Furthermore, excess body weight or particular patterns of body fat distribution can lead to illness such as cardiovascular disease and breast cancer.

The menopause is connected with a decline in the resting metabolic rate that minimizes the utilisation of calories and for this reason increases body weight.

A variety of researches have revealed that weight gain is biggest in the peri-menopausal years. There also appears to be a redistribution of fat mass at the time of the menopause, with an increase in the waist-to-hip ratio. Although it is a common belief that HRT inevitably causes weight gain, readily available proof recommends that this is not true. Indeed, some HRT programs, such as constant 17beta-oestradiol 2 mg/day integrated with sequential dydrogesterone 10 mg/day for 14 days/cycle (Femoston), may really help to prevent an increase in body fat mass and fat redistribution.

Notifying women about the results of the menopause on body weight/fat distribution and the possible beneficial impacts of some HRT programs need to assist to enhance HRT compliance.


Last modified: September 4, 2016


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