List of Painkillers

painkiller tablets

Pain is an undesirable sensation that might end up being discomforting at greater strengths. The typical websites or origin of pain are back, eye, face, stomach, joint pain, tongue etc. The triggered pain can be of different types like severe, moderate or even moderate. Several types of pain killers are readily available in the market to obtain rid of the pain. Pain killers are offered in pharmacy either as over-the-counter drugs however some may need prescription from a medical doctor. Below is the list of common pain relievers, both over-the-counter and prescribed, along with their effects, potency and adverse effects.

List of Painkillers with Reviews

General Guideline

  • Pain killers which are NSAIDs (nonsteroidal anti-inflammatory drugs) works on the patho-physiological processes that elicit pain, fever and other signs of swelling in the body.
  • Corticosteroids pain reliever are usually given for the management of musculoskeletal injuries due to its effect on shutting down inflammation causing processes.
  • The pain which is set off by any damaged or sensitive nerves (see most commonly in cases like sciatica or shingles) is generally handled by nerve blockers or anti-depressants. These tablets have the capacity to regulate the understanding of pain by main worried system.
  • Some pain- killers are made use of as muscle relaxants to decreases the intensity of pain triggered by the muscles group. This pain reliever serve as sedative for main worried system.
  • Factor behind consuming medication is to enhance the lifestyle. It is essential to recognize that every pain reliever is connected with some negative effects in short term or long term. Therefore it is encouraged to learn and determine potential drawbacks prior to taking in any painkiller.

Following are the description of a few of the pain reliever:


It is among the popular pain killers readily available (primarily utilized for the management of common headaches and non nerve discomforts). The efficient dosage is 2 tablets which can be consumed a minimum of 4 times a day (or at every 6 hrs interval). This dose and dosing routine is thought about safe for grownups. There are no common adverse effects for this medication and this drug can be used for longer time period. Nevertheless overdose of paracetamol can trigger some serious negative effects; for that reason it is highly recommended not to increase the dosage if the intensity of pain increases. If pain symptoms cannot resolve within 3 days, get in touch with the basic physician.


This drug is a type of NSAIDs i.e. non steroidal anti inflammatory drugs. It works best on inflammation triggering drugs in a very same method it is used for dealing with arthritis or any injury. This drug is not enabled to be made use of for longer time periods unless the swelling does not vanish. If this drug is consumed for longer time periods, it can result in significant adverse effects like bleeding, indigestion, heart problems and kidney issues. It is highly encouraged not to take in overdose of this drug as it can trigger severe repercussions.


This drug does not work well alone but can provide far much better results when used with paracetamol in a single formulation. Over the counter drugs are available under the label of co-codamol (which is paracetamol integrated with lower amount of codeine). Greater potency of codeine should just be utilized on doctor’s prescription. Some other painkillers with greater potency consist of Zydol (tramadol) and dihydrocodeine.

Drugs under this category are considered as habit-forming or addicting. The factor behind is these drugs makes an individual feel unhealthy for a short time duration when stop taking in. If for any certain factor this drug is consumed for longer period then consult your basic doctor for suggestions.

Amitriptyline and Gabapentin

Gabapentin is the drug used for dealing with epilepsy and amitriptyline medication and is used for dealing with anxiety. Both of the drugs are also given to patients for dealing with pain activated by damaged or hyper-sensitive nerves that includes sciatica, shingles or nerve pain caused by diabetes. This medication is taken in when prescribed by the general doctor. Adverse effects of both the drugs consist of dizziness and drowsiness.


This drug is thought about as effective and best pain reliever offered. Some other drugs fall under this classification consist of fentanyl, buprenorphine and Oxycodone. It is encouraged to book using this pain killer just in severe pain. These medications are only consumed when recommended by pain professional or general physician as the doctor will keep an eye on the development on dosage potency. These drugs are typically used for long term to administer the pain.

Strong opioids are medicines used to deal with severe or long-lasting (persistent) pain. Although there are numerous kinds of strong opioids, morphine is the most frequently utilized strong opioid and usually the first one your doctor will prescribe, according

Oxymorphone hydrochloride extended-release tablets are suggested for the management of pain severe sufficient to require daily, ongoing, long-term opioid treatment and for which alternative treatment choices are insufficient.

The most typical side-effects are constipation, feeling sick (queasiness), and tiredness. It is uncommon for individuals who take a strong opioid to deal with pain to become addicted to strong opioids.

The following table lists more OTC and recommended painkillers:

List of Painkillers by strength (from strongest to weakest)

OTC Pain Killers
Brand Name
Generic Name
Per Pill Dose
Best Uses
Aspirin (also classified under
NSAIDs or acetylsalicylic acid)
81 mg
325 mg
Helpful for the management of pains and minor aches
L374 caplet
500 mg
Treat fever, can be used instead of aspirin if a person is allergic to salicylates or aspirin, given to arthritis patients, treat rheumatism and musculo-skeletal issues
Combination of acetaminophen and aspirin (NSAID)
325 mg
500 mg
Given for the acute management of headache
44 291 tablet
200 mg
Treat muscle aches and fever
naproxen sodium
(one of the very potent and powerful anti-inflammatory agents)
220 mg
Prescribe mainly for the management of arthritis pain and inflammation. It is also effective for other
musculo-skeletal ailments
Motrin 800
(effectively used as an antipyretic, and analgesic).
Classified under NSAIDs
220 mg
800 mg
Treat rheumatism, arthritis and musculo-skeletal issues

Prescription Pain Killers
Brand Name
Generic Name
Per Pill Dose
Best Uses
Problems Caused
(COX-2 inhibitor)
100 mg
200 mg
Rheumatoid, osteoarthritis and other sources of acute pain in addition to menstruation pain
Moderately increase the risk of bleeding in stomach, stroke and
heart attack
50 mg
Gives relief from moderate pain
Constipation, nausea, dizziness, drowsiness, headache and vomiting
* NOTE: when the study is conducting Ultram and Celebrex does not exist. Their scores are an estimation
Meperidine HCl
50 mg
100 mg
Opiates drug and synthetic opiates drugs are considered as the most powerful pain killers, but their use is abuse as all these drugs can make a person habitual of it.
Including large quantity of Tylenol (acetaminophen) with these drugs is prohibited for pharmaceutical companies and the reason behind is its overdose can totally destroys liver.
** The strength of Norco is an estimation as it does not exist while study was conducting.
Acetaminophen and hydrocodone
5 mg to
500 mg
Acetaminophen and hydrocodone
5 mg to
500 mg
Lorcet Plus
Acetaminophen and hydrocodone
7.5 mg to
650 mg
Vicodin ES
Acetaminophen and hydrocodone
7.5 mg to
750 mg
Acetaminophen and hydrocodone-APAP
5 mg to 325 mg
10 mg to 325 mg
Acetaminophen and hydrocodone
10 mg to 500 mg
Vicodin HP
Acetaminophen and hydrocodone
10 mg to 660 mg
Acetaminophen and oxycodone HCl
2.5 mg to 650 mg
Oxycodone is considered as powerful and very effective.
NOTE: The strength of oxycodone is an estimation as it does not exist when study was conducted
Aspirin, oxycodone, terephthalate oxycodone HCl
325 mg
4.50 mg
0.38 mg
Oxycontin 40
Oxycodone HCl
40 mg
MS Contin RMS
15 mg
100 mg
It is considered as the 4th most powerful drug available.
5mg 7.5mg
10mg 15mg
20mg 30mg 40mg
Oxymorphone hydrochloride extended-release tablets are suggested for the management of pain severe sufficient to require daily, ongoing, long-term opioid treatment and for which alternative treatment choices are insufficient.
Fentora Duragesic
Lollipop or Skin patch
The strength of fentanyl is the result of an estimate since it was not developed when study was conducted. It is a powerful substance for treating fragmentation and gunshot wounds. The overdosage is associated with serious side effects and consequences. It is highly recommended to handle fentanyl carefully as mishandling can lead to death due to respiratory depression.
1 mg
2 mg
3 mg
4 mg
Dilaudid is considered as more effective as compared to morphine with some serious side effects



Updated: September 7, 2016 — 1:45 am

The Author

Reyus Mammadli

Healthy lifestyle advisor. Bachelor Degree of Medical Equipment and Electronics.
  • David Rodgers

    Obviously, one can’t always get every option onto a table like this but I believe that Oxymorphone is conspicuously missing.

    • Angie Baumgartner

      Yes it is i wonder where it fits in because that’s what i take !

    • Thanks for reminder. Opana (Oxymorphone) was added to the list.

  • Paul M Hucik

    I would say that Fentanyl is the strongest, with Opana as number 2, and Oxycodone as number 3.

    • Kitten

      People mistakenly believe fentanyl to be the strongest but it is actually dilaudid.

      • Derrick

        I would have to respectively disagree, as I have personal experience with everything on this list and can say with confidence that Paul is correct!

  • Tagir Taring

    what about Dolo 650

    • It is Acetaminophen, which already mentioned in the list.

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  • Roy Smith

    What about acetaminophen with Codeine aka T-3

  • Goliath

    how many of them are available in india?

  • Logan

    Where are the Sufenta, Etorphine, and then the king Carfentanil. im sure the basic compounds are listed but these drugs are at the top, they are deadly, not so much Sufenta but the other 2 are adn probably cannot be consumed by humans without dying.

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